The Liver: Biology and Pathobiology, 6th Edition, edited by Irwin M. Arias, is a comprehensive and authoritative text that bridges the gap between basic scientific advances and the understanding of liver disease. This extensively revised edition remains a definitive resource in hepatology, integrating new discoveries in biomedical sciences and engineering with detailed insights into liver structure, function, and disease pathology and treatment.

Contributions from leading researchers delve into the cell biology of the liver, exploring its pathobiology, growth, regeneration, metabolic functions, and more. With 70 new chapters—including substantial original sections on liver cancer and groundbreaking advances that will significantly impact hepatology—this edition offers comprehensive, fully up-to-date coverage of both the current state and future direction of hepatology.

Topics include liver RNA structure and function, gene editing, single-cell and single-molecule genomic analyses, the molecular biology of hepatitis, drug interactions and engineered drug design, and liver disease mechanisms and therapies. Edited by globally-recognized experts in the field, this authoritative volume is essential reading for researchers, clinicians, and students interested in advancing their understanding of hepatology.