The Human Microbiota and Chronic Disease: Dysbiosis as a Cause of Human Pathology explores the intricate relationship between the human microbiota and chronic diseases, emphasizing how microbial dysbiosis can contribute to both bacterial infections and idiopathic chronic conditions. Edited by Luigi Nibali, this comprehensive text delves into the biology of microbial dysbiosis and its role in maintaining or disrupting human health.

Organized into five sections, the book covers a wide range of topics including the microbiota of the gut, oral cavity, and skin, with a focus on metagenomics as a key methodology for exploring these communities. It discusses the cellular, molecular, and genetic complexities of bacterial interactions within the human body and their impact on tissue homeostasis.

The text then examines the role of dysbioses in common bacterial diseases like periodontitis and bacterial vaginosis, along with potential dietary interventions to modulate microbiota composition. It further explores idiopathic diseases such as inflammatory bowel disease, diabetes, and obesity, hypothesizing how microbial imbalances might contribute to their development and progression.

Additionally, the book addresses therapeutic approaches aimed at manipulating the microbiota, including the use of probiotics, prebiotics, and fecal microbiota transplantation. It concludes with a forward-looking perspective on the future of medical treatment from a microbiota-centric viewpoint, offering insights into potential new treatments for chronic diseases.

By shedding light on these critical issues, this book serves as an essential resource for researchers, healthcare professionals, and students interested in understanding the complex interplay between human health and the microbial communities that inhabit our bodies.