The Heart of the Brain: The Hypothalamus and Its Hormones, authored by Gareth Leng, delves into the intricate workings of a critical yet relatively unknown part of the brain—the hypothalamus. This small structure plays a profound role in governing our physiology and behavior through its complex network of hormonal signals.

While humans often pride themselves on rational decision-making, Leng challenges this perspective by highlighting how much of what we do is driven by hormonal influences within the hypothalamus. The book examines the diverse array of neurons found in the hypothalamus, which communicate not just through neurotransmitters but also via potent hormones that have wide-reaching and long-lasting effects.

By exploring the evolutionary origins of these neurons and their hormone signals, Leng provides a comprehensive understanding of how the hypothalamus connects our passionate drives with rational thought. He delves into where the receptors for these hormonal signals are located within the brain, offering insights into how they regulate various bodily functions and behaviors.

Through accessible language and clear explanations, The Heart of the Brain showcases the significance of this often-overlooked part of the neuroendocrine system. It invites readers to reconsider the role that hormonal signals play in shaping our identity and actions, ultimately revealing how the hypothalamus is indeed at the heart of what makes us human.

Published by The MIT Press on July 31, 2018, with a print length of 280 pages, this book offers a detailed exploration of a critical aspect of neuroendocrinology. ISBN-13: 978-0262038058.