Schiff’s Diseases of the Liver, edited by Eugene R. Schiff, presents a comprehensive and evidence-based resource for hepatologists and gastroenterologists dealing with liver disease. This 12th edition, published on November 29, 2017, is the culmination of over five decades of excellence in liver literature. The book includes a companion website offering extensive supplementary materials. It covers essential topics such as anatomy, pathology, testing, imaging, and the impact of liver disease on other organs. Key features include treatment guidelines, management algorithms for various diseases, full-color illustrations, section overviews, concise key concept boxes, and a dedicated section on liver transplantation. This edition is thoroughly revised to ensure it remains current with the latest clinical advancements.