Molecular Pharming: Applications, Challenges and Emerging Areas is a comprehensive collection that surveys the exciting field of plant-made pharmaceuticals and industrial proteins. Authored by Allison R. Kermode (Editor), this first edition was published by Wiley-Blackwell on May 8, 2018, with ISBN-13: 978-1118801284. The book is divided into six sections, each exploring different aspects of the field.
The first three sections delve into the current status of plant biotechnology and advancements in plant platforms, strategies for improving yields, downstream processing, and controlling post-translational modifications of recombinant proteins. Section four reviews high-value industrial and pharmacological proteins produced in both established and emerging plant platforms. The fifth section addresses regulatory challenges facing the expansion of this field. Finally, the sixth section focuses on small molecule therapeutics, drug screening, plant specialized metabolites, and plants as model organisms for studying human disease processes.
This book offers in-depth coverage of molecular biology of plant expression systems and manipulation of glycosylation processes in plants; plant platforms, subcellular targeting, recovery, and downstream processing; plant-derived protein pharmaceuticals and case studies; regulatory issues; and emerging areas. It serves as an invaluable resource for researchers working in the field of plant molecular pharming, as well as for those conducting basic research in gene expression, protein quality control, and other subjects relevant to molecular and cellular biology.
