Kinomics: Approaches and Applications offers a comprehensive introduction to the field of kinome research. Authored by leading experts, the book covers major players and pathways that define the kinome, providing an essential overview for newcomers and established researchers alike. The bulk of the work delves into current strategies of kinome investigation and manipulation, including detailed discussions on kinase engineering, peptide substrate engineering, co-substrate design, and kinase inhibitor design. These methods are explored with a focus on their potential applications in kinome analysis and pharmacotherapy. This invaluable reference serves as a practical toolbox for every kinase researcher, offering a comparative analysis of current approaches to studying kinase action.