Fluid, Electrolyte and Acid-Base Physiology: A Problem-Based Approach by Kamel S. Kamel MD FRCPC offers a comprehensive guide on diagnosing and managing fluid, electrolytes, and acid-base disorders. This 5th edition, published in November 2016 by Elsevier, moves from basic physiology to practical clinical guidance, incorporating new discoveries and treatment options. The book is designed for nephrologists and emergency practitioners and includes questions and explanations for knowledge testing, margin notes, key point boxes, line drawings, diagnostic algorithms, and tables. Expert authors bring their experience in research, clinical practice, and education to make theoretical and clinical knowledge accessible. With 528 pages, it was selected for the 2025 Doody’s Core Titles® in Physiology.