Clinical Exercise Physiology, Fifth Edition, edited by Jonathan K. Ehrman, stands as a comprehensive and essential resource for healthcare professionals navigating the complexities of exercise management for chronic diseases and special populations. This seminal work, first published in 2003 and now in its fifth edition (released April 21, 2022), is meticulously designed to prepare students for critical clinical exercise certifications, including those from the ACSM-CEP, ACE (Medical Exercise Specialist), CSEP-CEP, and ESSA-AEP. Published by Human Kinetics, this text delves into 24 distinct chronic diseases and conditions, offering unparalleled depth and coverage. Each chapter thoughtfully explores the epidemiology, pathophysiology, clinical considerations, relevant drug and surgical therapies, and crucial exercise testing and prescription aspects for each chronic condition. Beyond specific diseases, dedicated chapters address exercise-related challenges for four key special populations. The Fifth Edition has been thoroughly revised and updated to reflect the very latest research, clinical guidelines, and position statements from leading professional organizations, ensuring its content remains at the forefront of the field.