Biochemistry: Concepts and Connections, by Dean R. Appling, Spencer J. Anthony-Cahill, and Christopher K. Mathews, is a first edition textbook published by Pearson on January 9, 2015. With ISBN-10: 321839927 and ISBN-13: 978-0321839923, this book offers a highly visual, precise, and fresh approach to guide today’s mixed-science majors to a deeper understanding of biochemistry. Designed for one or two-semester biochemistry courses, it engages students in the rapidly evolving field by better preparing them for the challenges of 21st-century science through quantitative reasoning skills and a rich, chemical perspective on biological processes. The text teaches the chemical logic underlying the mechanisms, pathways, and processes in living cells through groundbreaking biochemical art and a clear narrative that illustrates biochemistry’s relation to all other life sciences. Integration of biochemistry’s experimental underpinnings alongside the presentation of modern techniques encourages students to appreciate and consider how their understanding of biochemistry can and will contribute to solving problems in medicine, agricultural sciences, environmental sciences, and forensics.