Basic Principles of Drug Discovery and Development

By Benjamin E. Blass (Author)

Edition: 1st
Language: English
Publisher: Academic Press
Dimensions: 6 x 1.75 x 8.75 inches
ISBN-10: 012411508X
ISBN-13: 978-0124115088
Publication Date: May 11, 2015
Print Length: 580 pages

Description:

Basic Principles of Drug Discovery and Development presents the multifaceted process of identifying a new drug in the modern era, providing comprehensive explanations of enabling technologies such as high throughput screening, structure-based drug design, molecular modeling, pharmaceutical profiling, and translational medicine, all areas that have become critical steps in the successful development of marketable therapeutics. The text introduces fundamental principles of drug discovery and development, discussing important drug targets by class, in vitro screening methods, medicinal chemistry strategies in drug design, principles in pharmacokinetics and pharmacodynamics, animal models of disease states, clinical trial basics, and selected business aspects of the drug discovery process. It is designed to enable new scientists to rapidly understand key fundamentals of drug discovery, including pharmacokinetics, toxicology, and intellectual property.

Provides a clear explanation of how the pharmaceutical industry works
Explains the complete drug discovery process, from obtaining a lead to testing the bioactivity, to producing the drug, and protecting the intellectual property
Ideal for anyone interested in learning about the drug discovery process and those contemplating careers in the industry

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