The AGT Cytogenetics Laboratory Manual, Fourth Edition offers an in-depth exploration of the diagnostic tests and scientific principles underlying cytogenetics. Authored by Marilyn S. Arsham (Editor), this comprehensive guide is published by Wiley-Blackwell and was released on April 24, 2017. With a print length of 1168 pages and dimensions of 8.8 x 1.9 x 11.1 inches, the manual provides a rich compilation of laboratory-tested protocols currently in use at leading laboratories, along with practical advice for cytogeneticists.

Covering fundamental topics such as cell components, microscope usage, human tissue processing (including prenatal, constitutional, and neoplastic), laboratory safety, and the mechanisms behind chromosome rearrangement and aneuploidy, this manual has been updated to include new and expanded chapters by experts in the field. These additions encompass a unique collection of chromosome heteromorphisms, clinical examples of genomic imprinting, an example-driven overview of chromosomal microarray analysis, mathematics tailored for cytogeneticists, ISCN’s cytogenetic language for describing chromosome changes, tips on laboratory management, examples of laboratory information systems, and resources including internet and library materials. A special chapter is dedicated to animal chromosomes, catering to research and zoo cytogeneticists.

Designed as both a teaching resource for students in university or medical school settings and a peer-reviewed reference for researchers, clinicians, and lab professionals, this manual serves as an essential tool in the study of chromosome morphology, structure, pathology, function, and behavior. Its extensive content makes it a valuable asset for understanding and performing diagnostic tests in the cytogenetics laboratory environment.

ISBN-10: 9781119061229
ISBN-13: 978-1119061229